Bacteria and Chronic Infections Coursera All Weeks Quizes

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Week- 1

Module 1 Quiz


1. What is the difference between aerobic and anaerobic bacteria?


2. What is the difference between the Gram-positive and Gram-negative bacteria cells?


3. Is it possible for the same bacterium toexist both as planktonic and as biofilm?


4. What is the main difference between bacteria in planktonic and biofilm mode?


5. What is the most studied form of bacteria?


6. Can the same treatment be used on both planktonic and biofilm bacteria?


7. Which part of the infection pathogenesis is impaired in chronic infections?


8. Which of the following infections are due to biofilm formation?


9. How is an acute infection defined?


10. What causes the main pathology of acute bacterial infections?




Week- 2

Module 2 Quiz


1. What is the hallmark of a biofilm?


2. How can the tolerance of the biofilm be reversed?


3. Which part of the host response is important for the development of biofilm infections in the lungs of cystic fibrosis patients?


4. What is the inflammatory response a reaction to?


Question 5
What is consumed by the PMNs during the respiratory burst?


6. Which cell types accumulate in the synovial fluid in patients with device related prosthetic knee infection?


7. Which type of T-helper cell response is associated with mild lung disease in Cystic Fibrosis patients with chronic P. aeruginosa lung infection?


8. In which part of P. aeruginosa biofilms is ciprofloxacin acting bactericidal?


9. In which part of P. aeruginosa biofilms is colistin acting bactericidal?


10. What is the reasons for the adaptive tolerance in P. aeruginosa biofilms when treating with beta-lactam antibiotics?




Week- 3

Module 3 Quiz



1. Which of the following statements are true concerning the presence of bacteria in the human body?


2. Which of the following statements are true concerning environmental and commensal biofilms?


3. Which of the following bacteria are among the first to adhere to a clean tooth surface?


4. Which of the following virulence factors characterize cariogenic bacteria? (Pick 2)


5. Which of the following virulence factors are important concerning periodontitis? (Pick 2)


6. What is the causative factor to most common oral biofilm mediated diseases?


7. What is the disadvantage of molecular techniques for identification of skin microbiota?


8. Which part of the skin is the major physical barrier against invasion by microorganisms?


9. How often is normal epidermis renewed by shedding of dead skin cells?


10. Which of the following bacterial species are enhanced in growth by skin moisture?




Week- 4

Module 4 Quiz


1. What is the most correct definition of a chronic wound?


2. What is likely to be present in a wound that have a one-year history, heals very slowly and is very large?


3. Which bacterial species are likely to be present in wounds that heal very slowly, are very large or are older than one year?


4. What is the classical method in treatment of a late periprosthetic joint infection?


5. Which of the following is NOT considered a separate type of periprosthetic joint infection?


6. Which element is NOT part of the paradigm of typical periprosthetic joint infections?


7. From where do bacteria and viruses in the middle ear most often ascend?


8. What is Otitis media with effusion (OME)?


9. What is Chronic otitis media with suppuration (CSOM) characterized by?


10. Where has human middle ear biofilm infection/inflammation been evidenced?


11. The role of biofilm in middle ear infections is


12. What is Cystic fibrosis?


13. What is the most severe complication of patients suffering from Cystic fibrosis?




Week- 5

Module 5 Quiz


1. Are bacteria in biofilms unculturable?


2. How is the PK/PD parameters of beta-lactams changed in biofilms formed by bacteria producing beta-lactamase?


3. Which of the following antibiotics has a concentration-dependent killing in planktonic cells? (multible correct answers)


4. How can the development of antibiotic resistance in biofilms be prevented?


5. Where is bacterial biofilm situated in the chronic wound?


6. How can a carrier of local antibiotic diminish development of antibiotic resistance?


7. Which of the following limitations of laboratory culture are true in determining a biofilm associated infection?


8. Which of the following is NOT a criterion for biofilm infection?


9. Does in vitro biofilms always mimics biofilms in chronic infections?


10. What is most effective environmental change in the treatment of chronic infections?



Week- 6

Module 6 Quiz


1. What are ‘pathoadaptive genes’ ?


2. How can Pseudomonas aeruginosa by defined?


3. What does the concept of ‘within-host evolution’ refers to:


4. Which of the following methods/techniques has been instrumental for our understanding of ‘within-host evolution’?


5. What is the primary target of the antibiotic ‘Azithromycin’ ?


6. How is the ability of an organism to reproduce and survive described?


7. What does natural selection leads to?


8. Which one of these is important in maintaining cooperative traits in microorganisms?


9. When does variants with distinct colony morphology occur?


10. Which one of these types of social behaviour provides a fitness cost to the actor and a fitness benefit to the recipient of the behaviour ?


11. What is long-term co-existence important for?


12. Why might biofilm formation limit the spread of non-cooperative cheats?